Pqq what is

Pyrroloquinoline quinone is an anti-aging defense for the top energy-exhaustive organs. PQQ hinders the gene known as DJ-1 from self-oxidizing. Research shows that the mitochondria of a middle-aged person and that of an old person is usually highly damaged. PQQ boosts the health of the mitochondria and reverses this situation.

Pyrroloquinoline quinone hinders oxidative damage to the brain cells following ischemia-reperfusion injury the oxidative damage and inflammation that is caused by the immediate return of nutrients and blood to tissues deprived of them by a stroke.

PQQ also works effectively to protect your brain against any neurotoxicity that is induced by powerful toxins such as oxidopamine and mercury. PQQ protects neurons by inhibiting the damaging effects of prolonged over-stimulation of neurons usually associated with seizures and neurodegenerative diseases. It protects the neurons by adjusting the NMDA receptor site. PQQ promotes attention, cognition, and memory. When PQQ is taken together with coenzyme Q10, it improves the quality of life of old people as well as their mental status.

It also prevents or slows down the age-related cognitive decline that occurs among old and middle-aged people. Damage from a heart attack is usually inflicted via ischemia-reperfusion injury. PQQ supplements help reduce the size of the damaged areas resulting from an acute heart attack.

Studies carried out showed that this healing process occurs the whether PQQ is given before or after the heart attack. The supplements help reduce the size of the damaged areas and defend against heart muscle dysfunction.

This suggests that giving PQQ supplements to a heart attack victim within the initial hours of medical response can offer significant benefits to them. Mitochondrial dysfunction is widely recognized by scientists as a major biomarker of aging. Mitochondrial DNA possesses little protection against free radical damage, and therefore depends on antioxidants for protection. Its exceptional molecular stability is unlike that of other antioxidants because it allows PQQ to perform numerous electron transfers without going through a molecular breakdown.

PQQ is very effective in neutralizing hydroxyl and superoxide radicals, which are the two major causes of mitochondrial dysfunction. A study conducted at The University of California at Davis showed that PQQ is between 30 to 5, times more effective at sustaining mitochondrial energy production redox cycling than other antioxidant compounds such as Ascorbic Acid.

This process helps in improving human health and longevity. Apart from this process, the only other methods known to activate mitochondrial biogenesis in old people are strict caloric restrictions, intense aerobic exercises, and specific medications such as Metformin and Thiazolidinediones for diabetes. PQQ is an essential compound that plays a critical part in the human body.

Without it, a person can experience growth impairment, abnormal reproductive function, and compromised immune status. The immune system is very responsive to low amounts of PQQ and requires it just like other essential nutrients. PQQ effectively stimulates mitochondria repair, reproduction, and protection.

It also provides optimal defense against neural degeneration and gives powerful cardioprotection to ensure one lives a long and healthy life. In study 2, PQQ was administered as a daily dose 0. After 76 h, measurements included indices of inflammation [plasma C-reactive protein, interleukin IL -6 levels], standard clinical indices e.

The standard clinical indices were normal and not altered by PQQ supplementation. In Study 2, PQQ supplementation resulted in significant decreases in the levels of plasma C-reactive protein, IL-6 and urinary methylated amines such as trimethylamine N-oxide, and changes in urinary metabolites consistent with enhanced mitochondria-related functions.

However, the available research suggests that results may be seen from doses as low as 5 mg per day Yet, toxicology studies indicate that PQQ poses a risk of kidney damage when taken at very high doses No set dosage information for PQQ exists, and insufficient studies exist to fully examine its side effects.

Excessive doses may increase your risk of kidney damage. Eating plenty of PQQ-rich foods, such as spinach, parsley, carrots, oranges, tomatoes, bananas , dark chocolate, and green tea, is likely enough to get adequate amounts 1.

Still, PQQ supplements carry few risks. However, the risks of trying it are relatively low. While test-tube and animal studies indicate that PQQ may reduce inflammation and promote mitochondrial health, more research is needed. Chronic inflammation can lead to weight gain and disease.

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